Dopamine antagonist
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(Redirected from Antidopaminergic)
A dopamine antagonist is a drug which blocks dopamine receptors by receptor antagonism. There are five types of dopamine receptors in the human body; they are found in the brain, peripheral nervous system, blood vessels, and the kidney).
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[edit] Uses and examples
- Used as atypical antipsychotics (coupled with a serotonin antagonist): clozapine, risperidone, olanzapine, quetiapine, ziprasidone, aripiprazole
- Used as antiemetics: metoclopramide, droperidol, domperidone
- Used as tricyclic antidepressants: amoxapine
[edit] Side effects
- parkinsonism - due to effects on the nigrostriatal pathway
- hyperprolactinaemia - due to effects on the tuberoinfundibular pathway
- tardive dyskinesia (long term use)
[edit] Examples
Other examples include:[1]
- acepromazine
- amisulpride
- amoxapine
- azaperone
- benperidol
- bromopride
- butaclamol
- chlorpromazine
- chlorprothixene
- clopenthixol
- domperidone
- droperidol
- eticlopride
- flupenthixol
- fluphenazine
- fluspirilene
- haloperidol
- loxapine
- mesoridazine
- levomepromazine
- metoclopramide
- nafadotride
- nemonapride
- penfluridol
- perazine
- perphenazine
- pimozide
- prochlorperazine
- promazine
- raclopride
- remoxipride
- risperidone
- spiperone
- spiroxatrine
- stepholidine
- sulpiride
- sultopride
- tetrahydropalmatine
- thiethylperazine
- thioridazine
- thiothixene
- tiapride
- trifluoperazine
- trifluperidol
- triflupromazine
- ziprasidone
[edit] References
[edit] External links
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